• Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome 

      Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug; Saugstad, Ola Didrik; Berglund, Magnus M.; Strömberg, Patrik; Lau, Corinna; Espevik, Terje; Jansen, Johan Høgset; Castellheim, Albert; Mollnes, Tom Eirik; Barratt-Due, Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-27)
      <p><i>Background</i>: Meconium aspiration syndrome (MAS) is a severe lung condition affecting newborns and it can lead to a systemic inflammatory response. We previously documented complement activation and cytokine release in a piglet MAS model. Additionally, we showed ex vivo that meconium-induced inflammation was dependent on complement and Toll-like receptors.</p> <p><i>Objectives</i>: To ...
    • Neonatal Impedance Cardiography in Asphyxiated Piglets-A Feasibility Study 

      Berisha, Gazmend; Solberg, Rønnaug; Klingenberg, Claus Andreas; Solevåg, Anne Lee (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-25)
      Objectives: Impedance cardiography (ICG) is a non-invasive method for continuous cardiac output measurement and has the potential to improve monitoring and treatment of sick neonates. PhysioFlow® is a signal-morphology ICG-system showing promising results in adults with low and high cardiac output, but no data from neonates or neonatal models exist. The aim of this study was to investigate PhysioFlow® ...
    • Predictors of extubation success: a population-based study of neonates below a gestational age of 26 weeks 

      Ohnstad, Mari Oma; Stensvold, Hans Jørgen; Pripp, Are Hugo; Tvedt, Christine Raaen; Jelsness-Jørgensen, Lars-Petter; Astrup, Henriette; Eriksen, Beate Horsberg; Klingenberg, Claus Andreas; Mreihil, Khalaf; Pedersen, Tanja; Rettedal, Siren; Selberg, Terje Reidar; Solberg, Rønnaug; Støen, Ragnhild; Rønnestad, Arild Erland (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-09)
      Objective The aim of the study was to investigate first extubation attempts among extremely premature (EP) infants and to explore factors that may increase the quality of clinical judgement of extubation readiness. Design and method A population-based study was conducted to explore first extubation attempts for EP infants born before a gestational age (GA) of 26 weeks in Norway between 1 January ...